- Dr James Mittra
- Senior Lecturer and Head of Science, Technology, and Innovation Studies
- Room G.39 Old Surgeons' Hall High School Yards Edinburgh UK EH1 1LZ
- +44 (0)131 650 2453
- Research Interests
- Innovation, translational medicine, agrobiotechnology, Pharmaceuticals, risk governance, regulation, stratified medicine, genomics, Regenerative Medicine, Value, Public-private partnerships, collaboration, interdiciplinarity
Guidance and Feedback Hours
- By Appointment
With a background in sociology and philosophy, I have developed interdiciplinary research interests around innovation in life sciences, with a specific focus on translational research, regulation, and governance. I have been contributing to the development of new interdisciplinary methods and theories to better understand how ‘new biology’ is affecting the nature and process of health innovation and contributing to the global bioeconomy.
Through a series of related projects following my doctoral work on the impact of genetic knowledge on the life assurance industry, I explored the nature and practical implications of translational medicine and the changing organisation and management of health R&D . With colleagues in the Innogen Institute, I developed novel methods for studying business models and value systems for new technologies that do not have a conventional route to market, particularly in the field of regenerative medicine and stratified medicine.
More recently I have been exploring the concept of value (economic and non-economic aspects) in health-related innovation; particularly in the context of interdisciplinary and translational research where the distinction between public and commercial, and relationship between laboratory and clinic, has become blurred. This was all written up in my first monograph: The New Health Bioeconomy: R&D Policy and Innovation for the Twenty-first century (Palgrave Macmillan, 2016).
In April 2016, I was honoured to spend a week visiting the College of the Environment and Life Sciences at the University of Rhode Island as part of its Distinguished Visiting International Scholar programme.
My full CV can be viewed here
From January, 2018 I will be Head of the Science, Technology and Innovation Studies Subject Group. Previously I have been Deputy Director (Research) of the Graduate School of Social and Political Science (2015-2017); Director of the MSc in Management of Bioeconomy, Innovation and Goverance (BIG) (2014-2017) Deputy Director of the Innogen Institute (2014-2017); and Postgraduate Research Advisor (admissions) for STIS (2014-2015) when I also convened the Science, Technology and Innovation Studies Pathway for the Scottish Graduate School of Social Science.
BA (Hons) Sociology and Philosophy (MMU 1997)
MA Sociology (University of Leeds 1998)
PhD Sociology (University of Warwick 2004)
My ORCID idenitfier is: 0000-0002-0185-6770
Mittra, J. (2016) The New Health Bioeconomy: R&D Policy and Innovation for the Twenty-first Century: (Basingstoke: Palgrave Macmillan)
This book provides original insights into how "new biology" and "translational" policies to drive a health bioeconomy are reshaping innovation ecosystems, and disrupting R&D practices, institutional and professional boundaries, and notions of "value" in healthcare. Drawing on rich empirical data, the author argues for a definition of value beyond the economic to better understand these transformative changes and reflect on the bioeconomy's future.
Chapter 1 available here
Review in New Genetics and Society here
Mittra, J & C. Milne (eds) (2013) Translational Medicine: The Future of Therapy?, (Singapore: Pan-Stanford)
This book brings together a range of academic, industry and practitioner perspectives on translational medicine (TM). It enhances conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic research, therapeutic development, and institutional infrastructure. In recognition of the various implications TM has for public health policy and commercial innovation, the book addresses the major systemic aspects of the field.
Peer Reviewed Articles
Wield, D., Tait., J., Chataway, J., Mittra, J., and Mastroeni, M. (2017) ‘Conceptualising and practising multiple knowledge interactions in the life sciences’, Technological Forecasting and Social Change, 116, pp. 308-315
Milne, C-P., Mittra, J., Kojima, N., Sugiyama, D., Awatin, J., and Simmons, G. (2016) 'Prospects for Harmonizing Regulatory Science Programs in Europe, Japan, and the United States to Advance Regenerative Medicine', Therapeutic Innovation and Regulatory Science, 50 (6): 724-733
Mittra. J., J. Tait., M. Mastroeni., M. Turner., J. Mountford., K. Bruce. (2015) ‘Identifying Viable Regulatory and Innovation Pathways for Regenerative Medicine: A Case Study of Cultured Red Blood Cells', New Biotechnology, 32 (1): 180-190
Mittra, J. (2013) ‘Repairing the ‘Broken Middle’ of the Health Innovation Pathway: Exploring Diverse Practitioner Perspectives on the Emergence and Role of ‘Translational Medicine’, Science and Technology Studies, 26 (3)
Wield, D., R. Hanlin, J. Mittra & J. Smith (2013) ‘Twenty-First Century Bioeconomy: Global Challenges of Biological Knowledge for Health and Agriculture’, Science and Public Policy, 40, pp. 17-24
Mittra, J & J. Tait (2012) ‘Analysing Stratified Medicine Business Models and Value Systems: Innovation-Regulation Interactions’, New Biotechnology, 29 (6), pp. 709-719
Mittra, J., J. Tait & D. Wield (2011) ‘From Maturity to High Value-Added Innovation : Lessons from the Pharmaceutical and Agro-Biotechnology Industries’, Trends in Biotechnology, 29 (3), pp. 105-109
Mittra, J., J. Tait & D. Wield (2011) ‘The Future of Pharmaceutical Innovation: New Challenges and Opportunities’, Innovations in Pharmaceutical Technology, March 2011, pp. 32-34
Mittra, J. (2008) ‘Impact of the Life Sciences on Organisation and Management of R&D in Large Pharmaceutical Firms’, Int. J. Biotechnology, 10 (5), pp. 416-440
Mittra, J. (2007) ‘Predictive Genetic Information and Access to Life Assurance: The Poverty of Genetic Exceptionalism’, Biosocieties, 2 (3), pp. 349-373
Mittra, J. (2007) ‘Marginalising Eugenic Anxiety through a Rhetoric of Liberal Choice: A Critique of the House of Commons Select Committee Report on Reproductive Technologies’, New Genetics and Society, 26 (2), pp. 159-179
Mittra, J. (2007) ‘Life Science Innovation and the Re-structuring of the Pharmaceutical Industry: Merger, Acquisitions and Strategic Alliance Behaviour of Large Firms', Technology Analysis and Strategic Management, 19 (3), pp. 279-301
Mittra, J. & R. Williams (2007) ‘Evolution of the Life Science Industries’, Technology Analysis and Strategic Management, Special Issue, 19 (3), pp. 251-255
Mittra, J. (2006) ‘The Socio-Political Economy of Pharmaceutical Mergers: A Case study of Sanofi and Aventis', Technology Analysis and Strategic Management, 18 (5), pp. 473-496
Mittra, J. (2006) ‘Genetic Exceptionalism and Precautionary Politics: Regulating for Uncertainty in Britain's Genetics and Insurance Policy Process', Science and Public Policy, 33 (8) pp. 585-600
Gardner, J., Webster, A., and Mittra, J. (2017) ‘ The ‘Entrepreneurial State’ and the Leveraging of Life in the Field of Regenerative Medicine’, in Pavone, P., and Goven. J (eds) Bioeconomies: Life, Technology and Capital in the 21st Century, (Basingstoke: Palgrave Macmillan)
Milne, C.P, & J. Mittra. (2015) ‘Is Translational Medicine the Future of Therapy?’, in R. Bawa (Editor), G. F. Audette and B. E. Reese. (Assistant Editors): Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety and Risk, Pan Stanford Publishing, Singapore, pp. 997-1012
Mittra, J (2013) ‘Exploiting Translational Medicine through Public-Private Partnerships: a Case Study of Scotland’s Translational Medicine Research Collaboration (TMRC)’, In Mittra & Milne (eds) Translational Medicine: The Future of Therapy? 2013, Pan-Stanford: Singapore, pp. 213-229
Mittra, J. & C. Milne (2013) ‘Introduction to Translational Medicine’, in Mittra & Milne (eds) Translational Medicine: The Future of Therapy? 2013, Pan-Stanford: Singapore, pp. 3-13
Tait, J., Bruce, A., Mittra, J., Purves, J., and Scannell, J. (2014) Independent Review on Antimicrobial Resistance: Regulation-Innovation Interactions and the Development of Antimicrobial Drugs and Diagnostics for Human and Animal Diseases, Main Report for ESRC Innogen Institute
Mittra, J., M. Mastroeni & J. Tait (2014) Engaging with Uncertainty and Risk in Agricultural Biotechnology Regulation: Delivering Safety and Innovation, Final Report of ESRC/Syngenta Knowledge Exchange Project
Omidvar, O., M. De Grijs., D. Castle, J. Mittra., A. Rosiello and J. Tait (2014) Regenerative Medicine: Business Models, Venture Capital and the Funding Gap, Report on ESRC Project, ‘New Funding Models for Regenerative Medicine’ ESRC Innogen Centre/Innogen Institute
Mastroeni, M., J. Mittra & J. Tait (2012) Methodology for the Analysis of Life Science Innovation Systems (ALSIS) and its Application to Three Case Studies, Final Report of the Technology Strategy Board (TSB) Project REALISE, May 2012
Mittra, J., & Tait, J. (2009) ‘Stem Cells’, chapter for RiskBridge Report, SAS6-CT-2006-036661, pp. 224-268
Mittra, J (2009) ‘Risk Governance and Policy Learning Within and Between Risk Fields‘, Proceedings of the RiskBridge Final Conference ECFP6 Coordination Action
Refereed Working Papers
Mittra, J., M. Mastroeni., D. Wield., E. Barlow and K. Snowden (2014) ‘The Scottish Institutional Ecology of Health and Clinical/Medical Research and Key Issues for Scottish Independence’, Innogen Working Paper Number 109,
Haddow, G., J. Mittra., K. Snowden., E. Barlow and D. Wield (2014) ‘From “Sick Man” to “Living Lab”: The Narrative of Scottish Health Since Devolution’, Innogen Working Paper, Number 108, Series ESRC Future of the UK and Scotland.
Mastroeni, M., E. Barlow., J. Mittra., and D. Wield (2014) ‘The Imagined Health Community: Narratives of Scottish Health and Independence’, Innogen Working Paper, Number 112,
Yoruk, D. and Mittra, J. (2009) 'Mid Pharma: How Big is it and Where is it Going?, Innogen Working paper 81
Mittra, J (2003) ‘Innovation Processes in Genomics Industry Sectors’, Innogen Working Paper 548
Policy Briefs/Consultation Responses
Mittra. J., E. Barlow., M. Mastroeni., D. Wield., G. Haddow (2014) ‘The Implications of Scottish Independence for Healthcare and Medical Research’, Innogen Briefing Number 2, August 2014, Series ESRC Future of the UK and Scotland.
Mittra., J (2009) Innogen Response to Human Genetics Commission Enquiry into Direct to Consumer Genetic Tests, October 2009:
Mittra, J. (2009) Response to Nuffield Council Consultation Paper: Medical Profiling and Online Medicine: the ethics of healthcare in the molecular age, July 2009,
Mittra, J (2007) ‘Appropriate Governance of the Life Sciences: Regulation and Risk Governance of Stem Cell Therapies’, Innogen policy brief
Mittra, J. (2007) ‘Changing Strategies of Big Pharma’, Innogen Policy Brief
Tait, J, Mittra, J (2004) ‘Complexity and Innovation in the Pharmaceutical Industry’, Innogen policy brief
Mittra, J., G. Haddow and M. Mastroeni (2014) ‘Is Scottish Independence Bad for your Health?’ The Conversation, 12 August, 2014,
Mittra, J. (2009) ‘Translating Translational Medicine’, The Gen: The Newsletter of the ESRC Genomics Network, issue 10, p16-17.
Mittra, J. (2007) ‘GlaxoSmithKline and the Reorganization of R&D’, Innogen Case Study Prepared for Executive Development Programme, 25-27 April 2007
Mittra, J. (2007) ‘Herceptin and the Politics of Drug Regulation’, Innogen Case Study Prepared for Executive Development Programme, 25-27 April 2007
Tait, J., and Mittra, J. (2006) ‘Singing from the same Hymn Sheet: Can Genomics Harmonise with Chemistry?’ CHEManager, August, 2006, p. 14
Mittra, J. (2005) ‘Pharmaceutical Industries: Do They Prefer Treatment to Cure?’ The Biochemist 27 (3): 32-34
Tait, J. & Mittra. J. (2005) ‘Big Pharma: Coping with Complexity’, ESRC Genomics Network Newsletter, Issue 2, June 2005
Tait, J. & Mittra, J. (2004) ’Industry Challenges’, Chemistry and Industry, 6 December, 2004, No. 23, p. 24
Mittra, J. & J. Sulston (2004) ‘Genetics and Insurance: Should We Legislate?’ Genomics Network Newsletter, Issue 1, September 2004: 9-12
Mittra, J. (2016) ‘What is the Bioeconomy and How should we Value it?’, Invited Public Lecture, Distinguished Visiting International Scholar Programme, Ryan Family Auditorium, Center for Biotechnology and Life Sciences, University of Rhode Island, April 26th, 2016.
Mittra, J. (2016) ‘Challenges and Opportunities in Collaboration between the Natural and Social Sciences: Case studies from Regenerative Medicine and Agricultural Biotechnology’, Seminar talk to the Department of Environmental and Natural Resource Economics, the Coastal Institute Building, University of Rhode Island, April 29, 2016.
Mittra, J. (2016) ‘Preparing Students for Work in the Global Bioeconomy: The Need for Interdisciplinary Knowledge and Systems Thinking’, University of Rhode Island seminar talk to undergraduate scientists, April, 27th, 2016.
Mittra, J. (2015) ‘MSc in Management of Bioeconomy, Innovation and Governance: An Interdisciplinary Programme to Meet the Needs of the Bioeconomy’, 5th ICA Rectors and Deans Forum 2015, Faculty of Agricultural, Food and Environmental Sciences, Università Cattolica del Sacro Cuore, Piacenza, Italy, October 23rd, 2015
Mittra, J (2015) ‘Innovative Health and Scientific Research: Scotland within the UK: together or apart?’, Invited talk to Morningside Justice and Peace Group, The Open Door Café, Edinburgh, Feb 11, 2015
Mittra, J (2014) ‘Innovation/Regulation Interactions and Business Models for Antimicrobial Drug Development’, MRC workshop ‘Small molecule approaches to antibiotics – how can we enhance, develop and target’, May 25th, London
Mittra, J (2014) 'Innogen and the STRATIS Method: A Case Study of Cultured Red Blood Cells', Scottish Government Seminar, October 28, Edinburgh
Mittra, J, E. Barlow & M. Mastroeni (2014) ‘Is Scottish Independence Bad for your Health?’, Edinburgh International Fringe Festival, Beltane Cabaret of Dangerous Ideas, August 9th
Mittra, J (2014) ‘Scottish Independence and the Clinical Research System’, Scottish Independence and Health Workshop, Royal College of Physicians, Edinburgh, March 21
Mittra, J. (2014) ‘Business Models, Funding Gaps and New Value Systems for Regenerative Medicine’, Horizons in Human Cells International Conference, Edinburgh, May 28
Mittra, J (2013) ‘Identifying and Measuring Value(s) in Regenerative Medicine and Translational Research’, 'Dimensions of Value and Values Science, Technology and Innovation Studies: A Two Day Symposium and Advanced Training for Postgraduate Research Students’, University of Edinburgh, 17 and 18th April, 2013
Mittra, J (2012) ‘Repairing the Broken Middle of the Health Innovation Pathway: The Emergence of ‘Translational Medicine and its Impact on Organisational Practice’, Invited Keynote Lecture, International Conference on Translational Research in Biomedicine: Challenges and Good Practice’, November 19th, Berlin
Mittra, J., H. Lowrie., J. Tait & M. Maestroeni (2011) ‘Overcoming the Translational Gap in Commercialisation of Stem Cell Therapy’, Remedie Closing Conference: Bringing Regenerative Medicine to the Clinic: Trials and Tribulations in Europe and Beyond, April 18/19, Bilbao, Spain
Mittra, J & J. Tait (2012) ‘New Business Models and Value Systems in Regenerative Medicine’, Invited panel talk at MHRA Joint Workshop on the Regulation of UK Regenerative Medicine, October 30th, 2012
Mittra, J. (2010) Invited respondent at EGN Health Technologies and Health Systems Workstream, Workshop 3, Genomic subpopulations and health systems responses, November 11, University of Exeter
Mittra, J. (2008) ‘Interviewing Elite Groups in Biomedicine: Experiences from the Field’, PFGS Regional Meeting, Genomics Forum, University of Edinburgh, 14 April, 2008
Mittra, J. (2008) ‘Risk Governance of Stem Cells as Therapeutic Products and Broader Implications for Innovation’, PEALS Spring Symposium (The Identification, Regulation and Implications of Risk Within Stem Cell Research), 10-11 April, 2008, Durham Castle
Mittra, J. (2007) ‘’Risk Governance and Regulation of Stem Cells as Therapeutic Products’, Stem Cells: European Business Summit, Edinburgh, 12th October 2007 (paper also delivered at ESRC Genomics Network Conference, London, 25th October, 2007)
Mittra, J (2007) ‘Insurance and Healthcare in the Molecular Age’, invited discussant for Biodata, Health and Security Research Workshop, Institute for Advanced Studies, University of Lancaster, June 29th 2007
Mittra, J & J. Tait (2006) ‘Public-Private Partnerships in Translational Medicine: Scotland’s Translational Medicine Research Collaboration (TMRC)’, Paper presented at OECD Expert Workshop, ‘Emerging Research models for the Delivery of Health Innovation’, Paris, November 20-21 2006
Tait, J., and J. Mittra (2006) ‘Singing from the Same Hymn Sheet: Can Genomics Harmonise with Chemistry?’, SCIpharm, Wednesday 17 May 2006, Edinburgh International Conference Centre
Mittra, J (2005) 'Regulation of Human Reproductive Technologies in the UK: Libertarian Values Versus Communitarian Fears' – Norwegian Academy of Science and Letters, 16th September 2005 – Workshop organised by the Seminar in Science Studies, University of Oslo
I use interdisciplinary methods and analytical frameworks to improve understanding of the complex and dynamic ways in which the life sciences are affecting the nature and process of technological innovation within the pharmaceutical and healthcare sectors; the emergence and development of translational research; and risk-governance issues associated with the development of regenerative medicine and other advanced therapies.
My interests include:
- Impact of the life science and new biology on the pharmaceutical and biotechnology industries;
- New business models and value systems in the bioeconomy
- New approaches to value and pricing in healthcare
- Translational research and collaborative approaches to R&D;
- Risk governance and regulation of advanced therapies;
- Genetic risk, probability and insurance
- Stakeholder engagement with science and technology;
I am happy to supervise doctoral students wishing to explore these and related topics.
Regenerative Medicine and its Development and Implementation: An Analysis of Emergent Value Systems and Health Service Readiness (ESRC)
Riskbridge: Building Robust, Integrative Inter-disciplinary Governance Models for Emerging and Existing Risks
David Johnson (2016) ‘Regenerative Medicine Venturing: Entrepreneurial Behaviour and New Venture Development Under High Levels of Perceived Environmental Uncertainty’ (Supervised with the Business School)
Emma King (2013):’Innovation and regulation interactions in the development of clinical stem cell therapies’ (ESRC Case Student)
Donna Messner (2008): ‘Fast Track: The Transformation of Drug Approval and the Clinical Trial System for Drug Evaluation in the United States’
Sara Valencia-Cadavid (2014-) ‘Knowledge Management in the Outsourcing of Clinical Trials to Produce Vaccines in Global Alliances. Case study of Dengue Vaccine in Latin America’
Rosalind Attenborough (2015-) ‘Open Science as an Identity and Epistemic Virtue’ (ESRC funded)
I organise and/or teach the following taught postgraduate courses:
Introduction to Risk, Regulation and Governance
Regulation and Governance of the Life Sciences
Regulation and Governance of New Therapies (online)
Topics interested in supervising
I am interested in supervising students on a broad range of topics in health-related innovation, policy and regulation, including new empirical and theoretical approaches to the health-related bioeconomy and translational medicine; risk governance and regulation of new therapies; value(s) and valuation practices in health innovation; understanding new business models and commercialisation strategies in life science industries, and emergence of new R&D practices and stakeholder relations within life sciences. I am also interested in supervising projects in related sectors, where appropriate, such as agro-biotechnology.
If you are interested in being supervised by James Mittra, please see the links below for more information: