- Dr James Mittra
- Senior Lecturer and Head of Science, Technology, and Innovation Studies
- Science Technology and Innovation Studies School of Social and Political Science University of Edinburgh
- Room G.39 Old Surgeons' Hall High School Yards Edinburgh UK EH1 1LZ
- +44 (0)131 650 2453
- Research Interests
- Innovation, translational medicine, agrobiotechnology, Pharmaceuticals, risk governance, regulation, stratified medicine, genomics, Regenerative Medicine, Value, Public-private partnerships, collaboration, interdiciplinarity
Guidance and Feedback Hours
- By Appointment
With an undergraduate background in Humanities and Social Science, followed by postgraduate work in sociology and science and technology studies (STS), I have developed interdisciplinary research interests around innovation in life sciences, with a specific focus on translational research, regulation, and risk-governance. I have been contributing to the development of new interdisciplinary methods and theories to better understand how ‘new biology’ is affecting the nature and process of health innovation and contributing to the global bioeconomy.
Through a series of related projects following my doctoral work on the impact of genetic knowledge on the life assurance industry, I explored the nature and practical implications of translational medicine and the changing organisation and management of health R&D . With colleagues in the Innogen Institute, I have developed novel methods for studying business models and value systems for new technologies that do not have a conventional route to market, particularly in the field of regenerative medicine and stratified medicine.
More recently I have been exploring the concept of value (economic and non-economic aspects) in health-related innovation; particularly in the context of interdisciplinary and translational research where the distinction between public and commercial, and relationship between laboratory and clinic, has become blurred. This was written up in my first monograph: The New Health Bioeconomy: R&D Policy and Innovation for the Twenty-first century (Palgrave Macmillan, 2016).
In April 2016, I was honoured to spend a week visiting the College of the Environment and Life Sciences at the University of Rhode Island as part of its Distinguished Visiting International Scholar programme.
In 2018 I successfully completed the Edinburgh Teaching Award and became a Senior Fellow of the UK Higher Education Authority (SFHEA)
I am currently Head of the Science, Technology and Innovation Studies Subject Group. Previously I have been Deputy Director (Research) of the Graduate School of Social and Political Science (2015-2017); Director of the MSc in Management of Bioeconomy, Innovation and Goverance (BIG) (2014-2017) Deputy Director of the Innogen Institute (2014-2017); and Postgraduate Research Advisor (admissions) for STIS (2014-2015), when I also convened the Science, Technology and Innovation Studies Pathway for the Scottish Graduate School of Social Science.
BA (Hons) Humanities and Social Science (Sociology with Philosophy) (MMU 1997)
MA Sociology (University of Leeds 1998)
PhD Sociology (University of Warwick 2004)
Edinburgh Teaching Award (Senior Fellow of the Higher Education Authority) (2018)
Innovation, translational medicine, agrobiotechnology, Pharmaceuticals, risk governance, regulation, stratified medicine, genomics, Regenerative Medicine, Value, Public-private partnerships, collaboration, interdiciplinarity
My interests include:
- - Impact of the life science and new biology on the pharmaceutical and biotechnology industries;
- - New business models and value systems in the bioeconomy
- - New approaches to value and pricing in healthcare
- - Translational research and collaborative approaches to R&D;
- - Risk governance and regulation of advanced technoogies
- - Genetic risk, probability and insurance
- - Stakeholder engagement with science and technology;
- I am happy to supervise doctoral students wishing to explore these and related topics.
I am currently writing up work from recently completed projects, and planning a book proposal on risk, uncertainty and the idea of progress.
Other Research Activities
INTERNATIONAL INVITED TALKS/KEYNOTES
- Mittra, J. (2016) ‘What is the Bioeconomy and How should we Value it?’, Public Lecture, Distinguished Visiting International Scholar Programme, Ryan Family Auditorium, Center for Biotechnology and Life Sciences, University of Rhode Island, April 26th, 2016.
- Mittra, J. (2016) ‘Challenges and Opportunities in Collaboration between the Natural and Social Sciences: Case studies from Regenerative Medicine and Agricultural Biotechnology’, Seminar talk to the Department of Environmental and Natural Resource Economics, the Coastal Institute Building, University of Rhode Island, April 29, 2016.
- Mittra, J. (2016) ‘Preparing Students for Work in the Global Bioeconomy: The Need for Interdisciplinary Knowledge and Systems Thinking’, University of Rhode Island seminar talk to undergraduate scientists, April, 27th, 2016.
- Mittra, J. (2015) ‘MSc in Management of Bioeconomy, Innovation and Governance: An Interdisciplinary Programme to Meet the Needs of the Bioeconomy’, 5th ICA Rectors and Deans Forum 2015, ‘Educating the Young Professionals to Feed the Planet & Provide for the Sustainable Bioeconomy’, Faculty of Agricultural, Food and Environmental Sciences, Università Cattolica del Sacro Cuore, Piacenza, Italy, October 23rd, 2015
- Mittra, J (2012) ‘Repairing the Broken Middle of the Health Innovation Pathway: The Emergence of ‘Translational Medicine and its Impact on Organisational Practice’, Invited Keynote Lecture, International Conference on Translational Research in Biomedicine: Challenges and Good Practice’, November 19th, Berlin
- Mittra, J., H. Lowrie., J. Tait & M. Mastroeni (2011) ‘Overcoming the Translational Gap in Commercialisation of Stem Cell Therapy’, Remedie Closing Conference: Bringing Regenerative Medicine to the Clinic: Trials and Tribulations in Europe and Beyond, April 18/19, Bilbao, Spain
- Mittra, J (2005) 'Regulation of Human Reproductive Technologies in the UK: Libertarian Values Versus Communitarian Fears' – Norwegian Academy of Science and Letters, 16th September – Workshop organised by the Seminar in Science Studies, University of Oslo
INVITED NATIONAL TALKS
- Mittra, J (2014) ‘Innovation/Regulation Interactions and Business Models for Antimicrobial Drug Development’, Invited by the Medical Research Council to speak at its workshop ‘Small molecule approaches to antibiotics – how can we enhance, develop and target’, part of its Tackling AMR’ A Cross Council Initiative, Tuesday 25 November, London
- Mittra, J. (2014) ‘Business Models, Funding Gaps and New Value Systems for Regenerative Medicine’, Horizons in Human Cells International Conference, Edinburgh, May 28
- Mittra, J & J. Tait (2012) ‘New Business Models and Value Systems in Regenerative Medicine’, Invited panel talk at MHRA Joint Workshop on the Regulation of UK Regenerative Medicine, October 30th
- Mittra, J. (2010) Invited respondent at EGN Health Technologies and Health Systems Workstream, Workshop 3, Genomic subpopulations and health systems responses, University of Exeter, November 11th
- Mittra, J. (2008) ‘Interviewing Elite Groups in Biomedicine: Experiences from the Field’, PFGS Regional Meeting, Genomics Forum, University of Edinburgh, 14 April
- Mittra, J. (2008) ‘Risk Governance of Stem Cells as Therapeutic Products and Broader Implications for Innovation’, PEALS Spring Symposium (The Identification, Regulation and Implications of Risk Within Stem Cell Research), 10-11 April, 2008, Durham Castle
- Mittra, J. (2007) ‘’Risk Governance and Regulation of Stem Cells as Therapeutic Products’, Stem Cells: European Business Summit, Edinburgh, 12th October 2007 (paper also delivered at ESRC Genomics Network Conference, London, 25th October
- Mittra, J (2007) ‘Insurance and Healthcare in the Molecular Age’, invited discussant for Biodata, Health and Security Research Workshop, Institute for Advanced Studies, University of Lancaster, June 29th
- Mittra, J & J. Tait (2006) ‘Public-Private Partnerships in Translational Medicine: Scotland’s Translational Medicine Research Collaboration (TMRC)’, Paper presented at OECD Expert Workshop, ‘Emerging Research models for the Delivery of Health Innovation’, Paris, November 20-21
- Tait, J., and J. Mittra (2006) ‘Singing from the Same Hymn Sheet: Can Genomics Harmonise with Chemistry?’, SCIpharm, Wednesday 17 May, Edinburgh International Conference Centre
- Banda, G., Tait, J., and Mittra, J (2017) ‘Regenerative Medicine Business models’, Regenerative Medicine in the UK Health System, Final conference of the ESRC REGenableMED Project, King’s College London, May 23rd
- Mittra, J. (2017) ‘Regulation and Governance of Advanced Therapies’, 3rd European Technology Assessment Conference, University of Cork, May 18th
- Mittra, J. (2017) ‘Structured Support for Doctoral Training in the Graduate School of Social and Political Science’, Benchmarking the Important Elements of PhD Study Workshop, UK Council for Graduate Education, St Leanard’s Hall, University of Edinburgh
Mittra, J. (2015) ‘Innovative Health and Scientific Research: Scotland within the UK: together or apart?’, Invited presentation to the Morningside Justice and Peace Group, February 11, 2015, The Open Door Café, Morningside, Edinburgh
Mittra, J. (2014) ‘Innogen and the STRATIS Method: A Case Study of Cultured Blood Innovation’, Invited talk to Scottish Government, Edinburgh, October 24, 2014
Mittra, J. (2014) – Invited panel speaker (alongside 3 MSPs) at Edinburgh International Science Festival event ‘Choosing a Healthy Future’ (part of series of events linked to the independence referendum), National Museum of Scotland, April 10
Mittra, J, E. Barlow & M. Mastroeni (2014) ‘Is Scottish Independence Bad for your Health?’, Edinburgh International Fringe Festival, Beltane Cabaret of Dangerous Ideas, August 9th
- Mittra, J (2013) ‘Identifying and Measuring Value(s) in Regenerative Medicine and Translational Research’, 'Dimensions of Value and Values Science, Technology and Innovation Studies: A Two Day Symposium and Advanced Training for Postgraduate Research Students’, University of Edinburgh, 17 and 18th April
- Mittra, J. (2008) ‘Genetic Information and Access to Life Assurance; The Poverty of Genetic Exceptionalism’, EGN Network Conference, London, October 28
- Mittra, J. (2008) ‘Management Responses to Stem Cell Risks’, EC Riskbridge Workshop, Gorizia, Italy, May 13th
- Mittra, J. (2008) ‘Issue Framing in the Stem Cell Risk Field’, EC Riskbridge Workshop, Gorizia, Italy, May 12th
- Mittra, J. (2007) ‘Public-Private Partnerships to Exploit Translational Medicine: The Translational Medicine Research Collaboration (TMRC) and its Implications for the Future of Pharmaceutical Innovation’, ESRC Genomics Network Conference, London, 25th October
- Mittra, J. (2004) ‘The Merger of Sanofi and Aventis: The Encroachment of Politics on ‘Business Rationality’ – Innogen Retreat, University of Cranfield, 22 October
- Mittra, J. (2004) ‘Life Science Innovation and the Pharmaceutical Sector’, Innogen/Cesagen Joint Workshop, University of Edinburgh, 1 April
- Mittra, J. (2003) ‘Innovation Processes in Genomics-Related Industry Sectors’, Innogen Annual Retreat, The Burn, March 20
- Mittra, J. (2001) ‘Genetic Testing and Life Insurance: A Legislative Nightmare’, Postgraduate Forum on Genetics and Society 5th Colloquium, University of Nottingham, June 20
- Mittra, J. (2001) ‘The Use and Abuse of Biology: Eugenics, Evolutionary Psychology and the Future of Social Science’, Social Theory Seminar Series, Department of Sociology, University of Warwick, November 10
Guidance and Feedback Hours
I guest lecture on the first/second year course Science, Nature and the Environment.
I currently organise and teach the online course Regulation and Governance of New Therapies. This is an interdisciplinary, online course that equips students with in-depth knowledge and critical understanding of the regulation and governance of drug innovation, including both early stage R&D and translation of new science/technology to the clinic for public health benefit and the needs of the growing health bioeconomy. I also provide a guest lecture on the Biobusiness course.
I am interested in supervising students on a broad range of topics in health-related innovation, policy and regulation, including new empirical and theoretical approaches to the health-related bioeconomy; innovation, risk governance and regulation of advanced therapies; value(s) and valuation practices in health innovation; understanding new R&D practices and stakeholder relations within health systems; and global challenges in areas like antimicrobial resistance.
Find out more about the programmes that I am involved with:
Current PhD Students
Anna Couturier (2017-) 'Mapping the Impact of Algorithms on Digital Biocitizenship: A Case Study on Mesenchymal Stromal Cell-Derived Therapies'
Rosalind Attenborough (2015-) ‘Open Science as an Identity and Epistemic Virtue’ (ESRC funded)
Completed PhD Students
Sara Valencia-Cadavid (2018) ‘Knowledge Management in the Outsourcing of Clinical Trials to Produce Vaccines in Global Alliances. Case study of Dengue Vaccine in Latin America’
David Johnson (2016) ‘Regenerative Medicine Venturing: Entrepreneurial Behaviour and New Venture Development Under High Levels of Perceived Environmental Uncertainty’ (Supervised with the Business School)
Emma King (2013):’Innovation and regulation interactions in the development of clinical stem cell therapies’ (ESRC Case Student)
Donna Messner (2008): ‘Fast Track: The Transformation of Drug Approval and the Clinical Trial System for Drug Evaluation in the United States’
My ORCID idenitfier is: 0000-0002-0185-6770
Mittra, J. (2016) The New Health Bioeconomy: R&D Policy and Innovation for the Twenty-first Century: (New York: Palgrave Macmillan)
Chapter 1 available here
Review in New Genetics and Society here
Mittra, J & C. Milne (eds) (2013) Translational Medicine: The Future of Therapy?, (Singapore: Pan-Stanford)
Peer Reviewed Articles
Mittra, J., Bruce, A., Scannell, Jack W., and Tait, J. (2019) ‘The Role of the Regulatory System in Supporting Innovation Pathways for the Development of New Antimicrobial Drugs’, Technology Analysis and Strategic Management, (in press)
Mastroeni, M., Mittra, J., and Tait, J (2019) 'Political Influences on Biotechnology-based Innovation for European Agriculture: Risk-Assessment and Risk Management', Technology Analysis and Strategic Management (published online first)
Mittra, J., Mastroeni, M., Haddow, G., Wield, D., and Barlow, E. (2019) ‘Re-imagining Healthcare and Medical Research Systems in Post Devolution Scotland’, Sociological Research Online, 24 (1): 55-72
Mittra, J., and Zoukas, G. (2019) ‘Unpacking the Concept of Bioeconomy: Problems of Definition, Measurement and the Attribution of Value’, Science and Technology Studies (forthcoming, available online first)
Banda, G;, Tait, J;, and Mittra, J. (2018) 'Evolution of Business Models in Regenerative Medicine: Effects of a Disruptive Innovation on the Innovation Ecosystem', Clinical Therapeutics, 40 (7): 1084-1094
Wield, D., Tait., J., Chataway, J., Mittra, J., and Mastroeni, M. (2017) ‘Conceptualising and practising multiple knowledge interactions in the life sciences’, Technological Forecasting and Social Change, 116, pp. 308-315
Milne, C-P., Mittra, J., Kojima, N., Sugiyama, D., Awatin, J., and Simmons, G. (2016) 'Prospects for Harmonizing Regulatory Science Programs in Europe, Japan, and the United States to Advance Regenerative Medicine', Therapeutic Innovation and Regulatory Science, 50 (6): 724-733
Mittra. J., J. Tait., M. Mastroeni., M. Turner., J. Mountford., K. Bruce. (2015) ‘Identifying Viable Regulatory and Innovation Pathways for Regenerative Medicine: A Case Study of Cultured Red Blood Cells', New Biotechnology, 32 (1): 180-190
Mittra, J. (2013) ‘Repairing the ‘Broken Middle’ of the Health Innovation Pathway: Exploring Diverse Practitioner Perspectives on the Emergence and Role of ‘Translational Medicine’, Science and Technology Studies, 26 (3)
Wield, D., R. Hanlin, J. Mittra & J. Smith (2013) ‘Twenty-First Century Bioeconomy: Global Challenges of Biological Knowledge for Health and Agriculture’, Science and Public Policy, 40, pp. 17-24
Mittra, J & J. Tait (2012) ‘Analysing Stratified Medicine Business Models and Value Systems: Innovation-Regulation Interactions’, New Biotechnology, 29 (6), pp. 709-719
Mittra, J., J. Tait & D. Wield (2011) ‘From Maturity to High Value-Added Innovation : Lessons from the Pharmaceutical and Agro-Biotechnology Industries’, Trends in Biotechnology, 29 (3), pp. 105-109
Mittra, J., J. Tait & D. Wield (2011) ‘The Future of Pharmaceutical Innovation: New Challenges and Opportunities’, Innovations in Pharmaceutical Technology, March 2011, pp. 32-34
Mittra, J. (2008) ‘Impact of the Life Sciences on Organisation and Management of R&D in Large Pharmaceutical Firms’, Int. J. Biotechnology, 10 (5), pp. 416-440
Mittra, J. (2007) ‘Predictive Genetic Information and Access to Life Assurance: The Poverty of Genetic Exceptionalism’, Biosocieties, 2 (3), pp. 349-373
Mittra, J. (2007) ‘Marginalising Eugenic Anxiety through a Rhetoric of Liberal Choice: A Critique of the House of Commons Select Committee Report on Reproductive Technologies’, New Genetics and Society, 26 (2), pp. 159-179
Mittra, J. (2007) ‘Life Science Innovation and the Re-structuring of the Pharmaceutical Industry: Merger, Acquisitions and Strategic Alliance Behaviour of Large Firms', Technology Analysis and Strategic Management, 19 (3), pp. 279-301
Mittra, J. & R. Williams (2007) ‘Evolution of the Life Science Industries’, Technology Analysis and Strategic Management, Special Issue, 19 (3), pp. 251-255
Mittra, J. (2006) ‘The Socio-Political Economy of Pharmaceutical Mergers: A Case study of Sanofi and Aventis', Technology Analysis and Strategic Management, 18 (5), pp. 473-496
Mittra, J. (2006) ‘Genetic Exceptionalism and Precautionary Politics: Regulating for Uncertainty in Britain's Genetics and Insurance Policy Process', Science and Public Policy, 33 (8) pp. 585-600
Gardner, J., Webster, A., and Mittra, J. (2017) ‘ The ‘Entrepreneurial State’ and the Leveraging of Life in the Field of Regenerative Medicine’, in Pavone, P., and Goven. J (eds) Bioeconomies: Life, Technology and Capital in the 21st Century, (Basingstoke: Palgrave Macmillan)
Milne, C.P, & J. Mittra. (2015) ‘Is Translational Medicine the Future of Therapy?’, in R. Bawa (Editor), G. F. Audette and B. E. Reese. (Assistant Editors): Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety and Risk, Pan Stanford Publishing, Singapore, pp. 997-1012
Mittra, J (2013) ‘Exploiting Translational Medicine through Public-Private Partnerships: a Case Study of Scotland’s Translational Medicine Research Collaboration (TMRC)’, In Mittra & Milne (eds) Translational Medicine: The Future of Therapy? 2013, Pan-Stanford: Singapore, pp. 213-229
Mittra, J. & C. Milne (2013) ‘Introduction to Translational Medicine’, in Mittra & Milne (eds) Translational Medicine: The Future of Therapy? 2013, Pan-Stanford: Singapore, pp. 3-13
Tait, J., Bruce, A., Mittra, J., Purves, J., and Scannell, J. (2014) Independent Review on Antimicrobial Resistance: Regulation-Innovation Interactions and the Development of Antimicrobial Drugs and Diagnostics for Human and Animal Diseases, Main Report for ESRC Innogen Institute
Mittra, J., M. Mastroeni & J. Tait (2014) Engaging with Uncertainty and Risk in Agricultural Biotechnology Regulation: Delivering Safety and Innovation, Final Report of ESRC/Syngenta Knowledge Exchange Project
Omidvar, O., M. De Grijs., D. Castle, J. Mittra., A. Rosiello and J. Tait (2014) Regenerative Medicine: Business Models, Venture Capital and the Funding Gap, Report on ESRC Project, ‘New Funding Models for Regenerative Medicine’ ESRC Innogen Centre/Innogen Institute
Mastroeni, M., J. Mittra & J. Tait (2012) Methodology for the Analysis of Life Science Innovation Systems (ALSIS) and its Application to Three Case Studies, Final Report of the Technology Strategy Board (TSB) Project REALISE, May 2012
Mittra, J., & Tait, J. (2009) ‘Stem Cells’, chapter for RiskBridge Report, SAS6-CT-2006-036661, pp. 224-268
Mittra, J (2009) ‘Risk Governance and Policy Learning Within and Between Risk Fields‘, Proceedings of the RiskBridge Final Conference ECFP6 Coordination Action
Refereed Working Papers
Mittra, J., M. Mastroeni., D. Wield., E. Barlow and K. Snowden (2014) ‘The Scottish Institutional Ecology of Health and Clinical/Medical Research and Key Issues for Scottish Independence’, Innogen Working Paper Number 109,
Haddow, G., J. Mittra., K. Snowden., E. Barlow and D. Wield (2014) ‘From “Sick Man” to “Living Lab”: The Narrative of Scottish Health Since Devolution’, Innogen Working Paper, Number 108, Series ESRC Future of the UK and Scotland.
Mastroeni, M., E. Barlow., J. Mittra., and D. Wield (2014) ‘The Imagined Health Community: Narratives of Scottish Health and Independence’, Innogen Working Paper, Number 112,
Yoruk, D. and Mittra, J. (2009) 'Mid Pharma: How Big is it and Where is it Going?, Innogen Working paper 81
Mittra, J (2003) ‘Innovation Processes in Genomics Industry Sectors’, Innogen Working Paper 548
Policy Briefs/Consultation Responses
Mittra. J., E. Barlow., M. Mastroeni., D. Wield., G. Haddow (2014) ‘The Implications of Scottish Independence for Healthcare and Medical Research’, Innogen Briefing Number 2, August 2014, Series ESRC Future of the UK and Scotland.
Mittra., J (2009) Innogen Response to Human Genetics Commission Enquiry into Direct to Consumer Genetic Tests, October 2009:
Mittra, J (2007) ‘Appropriate Governance of the Life Sciences: Regulation and Risk Governance of Stem Cell Therapies’, Innogen policy brief
Mittra, J. (2007) ‘Changing Strategies of Big Pharma’, Innogen Policy Brief
Tait, J, Mittra, J (2004) ‘Complexity and Innovation in the Pharmaceutical Industry’, Innogen policy brief
Mittra, J., G. Haddow and M. Mastroeni (2014) ‘Is Scottish Independence Bad for your Health?’ The Conversation, 12 August, 2014,
Mittra, J. (2009) ‘Translating Translational Medicine’, The Gen: The Newsletter of the ESRC Genomics Network, issue 10, p16-17.
Mittra, J. (2007) ‘GlaxoSmithKline and the Reorganization of R&D’, Innogen Case Study Prepared for Executive Development Programme, 25-27 April 2007
Mittra, J. (2007) ‘Herceptin and the Politics of Drug Regulation’, Innogen Case Study Prepared for Executive Development Programme, 25-27 April 2007
Tait, J., and Mittra, J. (2006) ‘Singing from the same Hymn Sheet: Can Genomics Harmonise with Chemistry?’ CHEManager, August, 2006, p. 14
Mittra, J. (2005) ‘Pharmaceutical Industries: Do They Prefer Treatment to Cure?’ The Biochemist 27 (3): 32-34
Tait, J. & Mittra. J. (2005) ‘Big Pharma: Coping with Complexity’, ESRC Genomics Network Newsletter, Issue 2, June 2005
Tait, J. & Mittra, J. (2004) ’Industry Challenges’, Chemistry and Industry, 6 December, 2004, No. 23, p. 24
Mittra, J. & J. Sulston (2004) ‘Genetics and Insurance: Should We Legislate?’ Genomics Network Newsletter, Issue 1, September 2004: 9-12