School of Social and Political Science

Miguel Garcia-Sancho

Job Title

Senior Lecturer

Photo
Miguel Garcia-Sancho's photo

Room number

Room 2.95

Building (Address)

Old Surgeons' Hall

Street (Address)

High School Yards

City (Address)

Edinburgh

Country (Address)

UK

Post code (Address)

EH1 1LZ

Background

After his PhD at Imperial College London, Miguel worked at Manchester University, Centre for the History of Science, and the Spanish National Research Council (CSIC), Department of Science, Technology and Society. His research interests are in the history of contemporary biomedicine, with special emphasis on the transition between molecular biology and new forms of knowledge production at the fall of the 20th century:  biotechnology, bioinformatics and genomics. He is now a Senior Lecturer in the Department of Science, Technology and Innovation Studies of the University of Edinburgh and is leading a project entitled Medical Translation in the History of Modern Genomics, with funding from the European Research Council.

His research focuses on the history of concerted DNA mapping and sequencing initiatives, with special attention to the human and other large-scale genome projects that proliferated in the 1980s and 90s. He has also investigated the emergence of agricultural biotechnology and the cloning of Dolly the sheep. His book Biology, Computing and the History of Molecular Sequencing: From Proteins to DNA was published by Palgrave-Macmillan (2012, paperback edition in 2015). He previously worked as a journalist and is interested in science communication and public engagement.

See my latest publications and research projects here.

Undergraduate teaching

Honours course Controversies in Medicine, Technology and the Environment, also available to postgraduate students.

See video outlining the course's contents.

Publications

(2019, with D. Myelnikov) 'Between mice and sheep: biotechnology, agricultural science and animal models in late-twentieth century Edinburgh,' Studies in History and Philosophy of Biological and Biomedical Sciences, 75: 24-33. Published version / Postprint

(2016) 'The proactive historian: methodological opportunities presented by the new archives documenting genomics', Studies in History and Philosophy of Biological and Biomedical Sciences, 55: 70-82. Special issue on 'Navigating big biology', edited by Christine Aicardi and Miguel Garcia-Sancho. Published version / Postprint

(2016) Recasting the local and the global: the three lives of protein sequencing in Spanish biomedical research (1968-1998). In M. Merz and P. Sormani (eds.) The Local Configuration of New Research Fields: On Regional and National Diversity (Springer: Sociology of the Sciences Yearbook): 205-228. Published version / Postprint

(2015) 'Animal breeding in the age of biotechnology: the investigative pathway behind the cloning of Dolly the sheep', History and Philosophy of the Life Sciences, 37(3): 282-304. Published version / Postprint

(2015) ‘Genetic information in the age of DNA sequencing’, Information & Culture: A Journal of History, 50(1): 110-142. Published version / Postprint

(2012) Biology, Computing and the History of Molecular Sequencing: From Proteins to DNA, 1945-2000 (Basingstoke: Palgrave Macmillan).  Publisher's catalogue entry

(2012) From the genetic to the computer program: the historicity of data and computation in the investigations on the nematode worm C. elegans (1963-1998), Studies in History and Philosophy of Biological and Biomedical Sciences, 43: 16-28. Published version / Postprint

(2012, with P. Chow-White) Bi-directional shaping and spaces of convergence: interactions between biology and computing from the first DNA sequencers to global genome databases, Science, Technology and Human Values, 37(1): 124-164. Published version / 

(2011) From metaphors to practices: the introduction of information engineers into the first DNA sequence database, History and Philosophy of the Life Sciences, 33: 71-104. Published version / Postscript

(2011) Academic and molecular matrices: a study of the transformations of connective tissue research at the University of Manchester (1947-1996), Studies in History and Philosophy of Biological and Biomedical Sciences, 42(2): 233-245. Published version open access

(2010) A new insight into Sangers development of sequencing: from proteins to DNA, 1943- 77, Journal of the History of Biology, 43(2): 265-323. Published version / Postprint

(2007) The rise and fall of the idea of genetic information (1948-2006), Genomics, Society and Policy, 2(3): 16-36. Published version open access

(2007) Mapping and sequencing information: the social context for the genomics revolution, Endeavour, 31(1): 18-23. Published version / Postprint

Research interests

Research interests

History of science, science and technology studies, science communication, genomics, biotechnology, bioinformatics, animal genetics, biology and agriculture

My research interests include:

1) Interactions between biomedicine and computing / biology and agriculture.

2) The organisation of large-scale biomedical initiatives, especially genomic projects.

3) Changing configurations of pure and applied research in biotechnological enterprises.

4) Social and historical dimensions in the formation of biomedical expectations. Role of narratives and biographical accounts in those processes.

5) Interdisciplinary connections between history of science and contemporary-oriented science studies (anthropological, sociological, economic and policy perspectives).

Current projects

Medical Translation in the History of Modern Genomics.

Starting Grant, European Research Council (ERC). 1.5 million euros.

Completed projects

Historicising Dolly: An Edinburgh-centred case study of the emergence of animal biotechnology

UK Biotechnology and Biological Sciences Research Council (BBSRC) and University of Edinburgh. £200,000.

  • See published transcript of a Collective Memory Event that gathered the joint recollections of the scientists and stakeholders involved in the cloning of Dolly the sheep.
  • See project's final report.

PhD Topics

History of 20th century biomedicine, particularly:

1) History of animal or agricultural genetics;

2) Any aspect of the research career of Conrad Hal Waddington;

3) Historical or multidisciplinary studies of genomics in Asia, the US or Europe (especially France, Italy and Germany);

4) Interactions between global and local technoscience in countries traditionally considered as "peripheral", especially Southern and Eastern Europe;

5) Use of genetics and interactions between science, politics, medicine and society in the investigation of forced disappearances under totalitarian regimes and ancestry searches by "stolen babies".

Find out more about the programmes that I am involved with (opening in new windows):

Current PhD students

Second supervisor of Jose Gomez: Time, Expectations and the Future in Action in Ecuador's Yachay (first supervisor, Robin Williams)

Co-supervisor of Cristina MorenoAntimicrobial resistance protocols. Governance, hospital infrastructures and care practices in democratic Spain - 1970s-present (with Lukas Engelmann)

Co-supervisor of Jarmo de VriesThe influence of genomic medicine on clinical work and expertise (with Steve Sturdy and James Lowe)

Publications by user content

Publication Research Explorer link
Leng R, Viry G, Garcia Sancho Sanchez M, Lowe J, Wong M, Vermeulen N. The sequences and the sequencers: What can a mixed-methods approach reveal about the history of genomics? Historical Studies in the Natural Sciences. 2021 Apr 11.
Garcia Sancho Sanchez M, Leng R, Viry G, Wong M, Vermeulen N, Lowe J. The Human Genome Project as an exceptional episode in the history of genomics. Historical Studies in the Natural Sciences. 2021 Apr 11.
Garcia Sancho Sanchez M, Lowe J, Viry G, Leng R, Wong M, Vermeulen N. Yeast sequencing: 'Network' genomics and institutional bridges. Historical Studies in the Natural Sciences. 2021 Apr 11.
Lowe J, Garcia Sancho Sanchez M, Leng R, Wong M, Vermeulen N, Viry G. Across and within networks: Thickening the longue-durée history of genomics. Historical Studies in the Natural Sciences. 2021 Apr 11.
Garcia Sancho Sanchez M. The comparative and the experimental revisited. Acta Biotheoretica. 2021 Jan 26. https://doi.org/10.1007/s10441-020-09403-x
Garcia Sancho Sanchez M, Myelnikov D. Between mice and sheep: Biotechnology, agricultural science and animal models in late-twentieth century Edinburgh. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences. 2019 Jun 30;75:24-33. https://doi.org/10.1016/j.shpsc.2019.01.002
Garcia Sancho Sanchez M. Reordering life: Knowledge and control in the genomics revolution . New Genetics and Society. 2018 Dec;37(4):435-437. https://doi.org/10.1080/14636778.2017.1415139
Myelnikov D, Garcia Sancho Sanchez M, (ed.). Dolly at Roslin: A Collective Memory Event. Edinburgh: University of Edinburgh, 2017.
Garcia Sancho Sanchez M, Myelnikov D, Lowe J. The Invisible History of the Visible Sheep: How a Look at the Past may Broaden our View of the Legacy of Dolly. Biotechnology and Biological Sciences Research Council (BBSRC, UK), 2017. 20 p.
Garcia Sancho Sanchez M. The proactive historian: Methodological opportunities presented by the new archives documenting genomics. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences. 2016 Feb;55:70-82. https://doi.org/10.1016/j.shpsc.2015.09.005
Garcia Sancho Sanchez M, Aicardi C. Introduction: towards future archives and historiographies of ‘big biology’. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences. 2016 Feb;55:41-44. https://doi.org/10.1016/j.shpsc.2015.09.009
Garcia-Sancho M. Recasting the local and the global: the three lives of protein sequencing in Spanish biomedical research (1967-1995). In Merz M, Sormani P, editors, The Local Configuration of New Research Fields . Berlin: Springer. 2015. p. 205-228. (Sociology of the Sciences Yearbook). https://doi.org/10.1007/978-3-319-22683-5_12
Garcia-Sancho M. Animal breeding in the age of biotechnology: The investigative pathway behind the cloning of Dolly the sheep. History and Philosophy of the Life Sciences. 2015 Sep;37(3):282-304. https://doi.org/10.1007/s40656-015-0078-6
Garcia Sancho Sanchez M. Genetic information in the age of DNA sequencing. Information & Culture. 2015 Jan 15;50(1):110-142. https://doi.org/10.7560/IC50105
Garcia-Sancho M, González-Silva M, Santesmases MJ. Shaping biomedical objects across history and philosophy: A conversation with Hans-Jörg Rheinberger. Dynamis : Acta Hispanica ad Medicinae Scientiarumque Historiam Illustrandam . 2014;34(1):193-209.
Garcia-Sancho M. The Cybernetic Brain: Sketches of Another Future. Centaurus. 2013 Feb;55(1):59-61. https://doi.org/10.1111/1600-0498.12005
Chow-White PA, Garcia Sancho Sanchez M. Bidirectional Shaping and Spaces of Convergence: Interactions between Biology and Computing from the First DNA Sequencers to Global Genome Databases. Science, Technology, and Human Values. 2012 Jan;37(1):124-164. https://doi.org/10.1177/0162243910397969
Garcia Sancho Sanchez M. Biology, Computing, and the History of Molecular Sequencing: From Proteins to DNA, 1945-2000. Palgrave Macmillan, 2012. 256 p. (Science, Technology and Medicine in Modern History). https://doi.org/10.1057/9780230370937
Garcia Sancho Sanchez M. From the Genetic to the Computer Program: The Historicity of 'Data' and 'Computation' in the Investigations on the Nematode Worm C. elegans (1963-1998). Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences. 2012;43(1):16-28. https://doi.org/10.1016/j.shpsc.2011.10.002
Garcia Sancho Sanchez M. Academic and Molecular Matrices: A Study of the Transformations of Connective Tissue Research at the University of Manchester (1947–1996). Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences. 2011 Jun;42(2):233-245. https://doi.org/10.1016/j.shpsc.2010.12.007
Garcia-Sancho M. From metaphors to practices: The introduction of ‘information engineers’ into the first DNA sequence database. History and Philosophy of the Life Sciences. 2011;33:71-104. https://doi.org/http://www.hpls-szn.com/articles.asp?id=130&book=28
Garcia-Sancho M. A new insight into Sanger’s development of sequencing: From proteins to DNA, 1943-77. Journal of the History of Biology. 2010;43(2):265-323. https://doi.org/10.1007/s10739-009-9184-1
Garcia Sancho Sanchez M. Mapping and sequencing information: the social context for the genomics revolution. Endeavour. 2007 Mar;31(1):18-23. https://doi.org/10.1016/j.endeavour.2007.01.006
Garcia Sancho Sanchez M. The Rise and Fall of the Idea of Genetic Information (1948-2006). Genomics, Society and Policy. 2006;2(3):16-36.